Introduction to me and my projects

15 01 2012

Greetings from Tanzania! My name is Andrew Bouley. I am a third year medical student at Duke, and I am doing research abroad at the KCMC-Duke Collaboration in Moshi, Tanzania. This is my first DGHI blog.

For my first post, I wanted to describe my research projects. I am currently working on the three projects. The first project involves fever surveillance in northern Tanzanian hospitals as part of the Multi-Country Typhoid Fever Surveillance Program in sub-Saharan Africa (or TSAP). Typhoid fever, caused by Salmonella enterica serovar Typhi (S. Typhi), represents a significant global health burden. In Africa, typhoid fever persists as an endemic disease, yet the incidence of typhoid fever remains uncertain in many areas due to poor surveillance. Until better surveillance and diagnostic tools are applied to sub-Saharan Africa, national policies on vaccinations cannot be implemented in an evidence-based fashion. To this end, the KCMC-Duke Collaboration is working with the International Vaccine Institute to develop a better understanding of typhoid fever, paratyphoid fever, and non-typhoidal Salmonella (NTS). In the upcoming months, we are expanding the scope of this project to include bacterial zoonoses. Julian Hertz, another Duke medical student, is coordinating our TSAP efforts, while Holly Biggs, an infectious diseases fellow, is doing a lot of work with bacterial zoonoses, with an emphasis on leptospirosis. Dr. John Crump is the Duke PI for this project.

The second project that I am working on is analyzing data from a previous fever surveillance study at our site in Tanzania. The aim of this analysis is to produce a manuscript on the incidence and clinical characteristics of brucellosis.

The third project that I am assisting with has just started. It involves screening patients with HIV for Hepatitis B. Hepatitis B coinfection with HIV is poorly characterized in Tanzania, but some small studies from our site have found the incidence as high as 25% in certain populations. It is very important to obtain a better understanding of the true incidence of coinfection in northern Tanzania to guide screening and treatment management in Tanzania. For this project, I am working with Dr. Elizabeth Reddy as my mentor. Brianna Norton, an infectious diseases fellow, is spearheading this project.

Asanteni!

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One response

20 01 2012
Sarah

We can’t wait to read more!

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